Molecular markers for diagnostic cytology of neoplasms in the head region of the pancreas: mutation of K-ras and overexpression of the p53 protein product.

doi:10.1136/jcp.48.3.218

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Article

Molecular markers for diagnostic cytology of neoplasms in the head region of the pancreas: mutation of K-ras and overexpression of the p53 protein product.

Journal of clinical pathology - 1 Mar 1995

van Es J M, Polak M M, van den Berg F M, Ramsoekh T B, Craanen M E, Hruban R H, Offerhaus G J

Abstract excerpt

AIMS: To determine the potential efficiency of molecular markers specific for neoplastic change--mutations of the K-ras oncogene and the p53 tumour suppressor gene--in diagnosing pancreatic carcinoma. METHODS: Archival cytology samples obtained from 17 patients with established pancreatic carcino...

Topics

Adenocarcinoma
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
Female
Gene Expression
Genes, ras
Humans
Male
Middle Aged
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Proteins

Pancreatic Neoplasms

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Retrospective Studies

Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 7730480
DOI: 10.1136/jcp.48.3.218
PMCID: PMC502447

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7730480-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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