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Article

Molecular markers for diagnostic cytology of neoplasms in the head region of the pancreas: mutation of K-ras and overexpression of the p53 protein product.

Journal of clinical pathology - 1 Mar 1995

van Es J M, Polak M M, van den Berg F M, Ramsoekh T B, Craanen M E, Hruban R H, Offerhaus G J

Abstract excerpt

AIMS: To determine the potential efficiency of molecular markers specific for neoplastic change--mutations of the K-ras oncogene and the p53 tumour suppressor gene--in diagnosing pancreatic carcinoma. METHODS: Archival cytology samples obtained from 17 patients with established pancreatic carcinoma were assayed for alterations in K-ras and p53. To detect changes in p53 expression, immunocytochemistry with...

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Identifiers

PMID: 7730480
DOI: 10.1136/jcp.48.3.218
PMCID: PMC502447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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