Article
Mutation Profile and Fluorescence In Situ Hybridization Analyses Increase Detection of Malignancies in Biliary Strictures.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Jun 2017
Gonda Tamas A, Viterbo Domenico, Gausman Valerie, Kipp Claudine, Sethi Amrita, Poneros John M, Gress Frank, Park Tina, Khan Ali, Jackson Sara A, Blauvelt Megan, Toney Nicole, Finkelstein Sydney D
Abstract excerpt
BACKGROUND & AIMS: It is a challenge to detect malignancies in biliary strictures. Various sampling methods are available to increase diagnostic yield, but these require additional procedure time and expertise. We evaluated the combined accuracy of fluorescence in situ hybridization (FISH) and polymerase chain reaction-based DNA mutation profiling (MP) of specimens collected using standard brush techniques....
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