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Article

Polar transmembrane domains target proteins to the interior of the yeast vacuole.

Molecular biology of the cell - 1 Nov 2000

Reggiori F, Black M W, Pelham H R

Abstract excerpt

Membrane proteins transported to the yeast vacuole can have two fates. Some reach the outer vacuolar membrane, whereas others enter internal vesicles, which form in late endosomes, and are ultimately degraded. The vacuolar SNAREs Nyv1p and Vam3p avoid this fate by using the AP-3-dependent pathway, which bypasses late endosomes, but the endosomal SNARE Pep12p must avoid it more directly. Deletion analysis revealed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanine Nucleotide Exchange Factors

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Source

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Identifiers

PMID: 11071903
DOI: 10.1091/mbc.11.11.3737
PMCID: PMC15033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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