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Article

A dileucine-like sorting signal directs transport into an AP-3-dependent, clathrin-independent pathway to the yeast vacuole.

The EMBO journal - 1 May 1998

Vowels J J, Payne G S

Abstract excerpt

Transport of yeast alkaline phosphatase (ALP) to the vacuole depends on the clathrin adaptor-like complex AP-3, but does not depend on proteins necessary for transport through pre-vacuolar endosomes. We have identified ALP sequences that direct sorting into the AP-3-dependent pathway using chimeric proteins containing residues from the ALP cytoplasmic domain fused to sequences from a Golgi-localized membrane...

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Identifiers

PMID: 9564031
DOI: 10.1093/emboj/17.9.2482
PMCID: PMC1170590

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