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Article

Acidic di-leucine motif essential for AP-3-dependent sorting and restriction of the functional specificity of the Vam3p vacuolar t-SNARE.

The Journal of cell biology - 24 Aug 1998

Darsow T, Burd C G, Emr S D

Abstract excerpt

The transport of newly synthesized proteins through the vacuolar protein sorting pathway in the budding yeast Saccharomyces cerevisiae requires two distinct target SNAP receptor (t-SNARE) proteins, Pep12p and Vam3p. Pep12p is localized to the pre-vacuolar endosome and its activity is required for transport of proteins from the Golgi to the vacuole through a well defined route, the carboxypeptidase Y (CPY)...

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Identifiers

PMID: 9722605
DOI: 10.1083/jcb.142.4.913
PMCID: PMC2132875

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