Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast.

Molecular biology of the cell - 1 Apr 1996

Becherer K A, Rieder S E, Emr S D, Jones E W

Abstract excerpt

pep12/vps6 mutants of Saccharomyces cerevisiae are defective in delivery of soluble vacuolar hydrolases to the vacuole. Morphological analysis by electron microscopy revealed that pep12 cells accumulate 40- to 50-nm vesicles. Furthermore, pep12 cells have enlarged vacuoles characteristic of class D pep/vps mutants. PEP12 encodes a protein of 288 amino acids that has a C-terminal hydrophobic region and shares...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cloning, Molecular
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Molecular Sequence Data

Share to Phenotype

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 8730101
DOI: 10.1091/mbc.7.4.579
PMCID: PMC275911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast.PMID 8730101Read ↗

Pep3p/Pep5p complex: a putative docking factor at multiple steps of vesicular transport to the vacuole of Saccharomyces cerevisiae.Semantic proximity Read ↗

Pth1/Vam3p is the syntaxin homolog at the vacuolar membrane of Saccharomyces cerevisiae required for the delivery of vacuolar hydrolases.Semantic proximity Read ↗

Pep7p provides a novel protein that functions in vesicle-mediated transport between the yeast Golgi and endosome.Semantic proximity Read ↗

The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae.Semantic proximity Read ↗

Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant.Semantic proximity Read ↗

A family of small coiled-coil-forming proteins functioning at the late endosome in yeast.Semantic proximity Read ↗

Dynamin and clathrin are required for the biogenesis of a distinct class of secretory vesicles in yeast.Semantic proximity Read ↗

Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products.Semantic proximity Read ↗

The sodium/proton exchanger Nhx1p is required for endosomal protein trafficking in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

A selective transport route from Golgi to late endosomes that requires the yeast GGA proteins.Semantic proximity Read ↗

Polar transmembrane domains target proteins to the interior of the yeast vacuole.Semantic proximity Read ↗

An Arabidopsis syntaxin homologue isolated by functional complementation of a yeast pep12 mutant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.