Article
The OTF3 gene polymorphism confers susceptibility to psoriasis independent of the association of HLA-Cw*0602.
The Journal of investigative dermatology - 1 Nov 2000
Gonzalez S, Martinez-Borra J, Del Río J S, Santos-Juanes J, Lopez-Vazquez A, Blanco-Gelaz M, López-Larrea C
Abstract excerpt
Psoriasis has been strongly associated to HLA-Cw6, but it remains unclear whether Cw6 itself or a closely linked gene is associated with the disease. The aim of this study was to clarify whether the HLA-C itself determines disease susceptibility or whether it acts only as a marker for the susceptibility allele. We examined a sample of 95 type I psoriasis patients and 104 Spanish matched controls to investigate...
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