Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Psoriasis vulgaris and psoriatic arthritis share a 100 kb susceptibility region telomeric to HLA-C.

Rheumatology (Oxford, England) - 1 Sept 2003

Martínez-Borra J, González S, Santos-Juanes J, Sánchez del Rio J, Torre-Alonso J C, López-Vazquez A, Blanco-Geláz M A, López-Larrea C

Abstract excerpt

OBJECTIVE: To map the locus for susceptibility to psoriasis in patients with psoriatic arthritis. METHODS: Seventy-four patients with psoriatic arthritis and 95 patients with psoriasis vulgaris were included in this study. Polymorphic genes and microsatellite markers centromeric (C1_2_5) and telomeric (C1_4_4, OTF3, HCR and the corneodesmosin gene) to HLA-C were studied in an association analysis. Typing was also...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Psoriatic
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to HLA-C Antigens

Share to Microsatellite Repeats

Share to Polymorphism, Genetic

Share to Psoriasis

Share to Telomere

Source

Identifiers

PMID: 12730526
DOI: 10.1093/rheumatology/keg304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Psoriasis vulgaris and psoriatic arthritis share a 100 kb susceptibility region telomeric to HLA-C.PMID 12730526Read ↗

The region of 150 kb telometic to HLA-C is associated with psoriasis in the Jewish population.Semantic proximity Read ↗

Genetics of psoriasis and psoriatic arthritis.Semantic proximity Read ↗

HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype.Semantic proximity Read ↗

The OTF3 gene polymorphism confers susceptibility to psoriasis independent of the association of HLA-Cw*0602.Semantic proximity Read ↗

Association analysis using refined microsatellite markers localizes a susceptibility locus for psoriasis vulgaris within a 111 kb segment telomeric to the HLA-C gene.Semantic proximity Read ↗

Fine mapping of a psoriasis-susceptibility locus within the HLA class II region by using microsatellite markers in an association study of Japanese cases and controls.Semantic proximity Read ↗

Differential human leucocyte allele association between psoriasis and psoriatic arthritis: a family-based association study.Semantic proximity Read ↗

Patients with psoriatic arthritis may show differences in their clinical and genetic profiles depending on their age at psoriasis onset.Semantic proximity Read ↗

HLA-C locus alleles may modulate the clinical expression of psoriatic arthritis.Semantic proximity Read ↗

Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C.Semantic proximity Read ↗

A psoriasis vulgaris protective gene maps close to the HLA-C locus on the EH18.2-extended haplotype.Semantic proximity Read ↗

Analysis of 6 genetic loci for disease susceptibility in psoriatic arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.