Article
Comparison of clinical features of HLA-Cw*0602-positive and -negative psoriasis patients in a Han Chinese population.
Acta dermato-venereologica - 1 Jan 2007
Fan Xing, Yang Sen, Sun Liang Dan, Liang Yan Hua, Gao Min, Zhang Kai Yue, Huang Wei, Zhang XueJun
Abstract excerpt
HLA-Cw6 is strongly associated with psoriasis and has been suggested to be the PSORS1 gene that confers susceptibility to early-onset psoriasis. In this study of the clinical features of HLA-Cw*0602-positive and -negative psoriasis patients in a Han Chinese population, we typed HLA-C in a cohort of 679 patients and compared the two groups. Cw*0602-positive patients (n=345) had an earlier disease onset (p < 1 x...
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