Article
HLA-Cw*06 class I region rather than MICA is associated with psoriatic arthritis in Czech population.
Rheumatology international - 1 Sept 2009
Fojtíková Markéta, Stolfa Jirí, Novota Peter, Cejková Pavlína, Dostál Ctibor, Cerná Marie
Abstract excerpt
Psoriatic arthritis (PsA) is a chronic inflammatory joint disease which affects patients suffering from psoriasis. The genetic background especially the susceptibility loci on the short arm of the chromosome six contribute to PsA development. In our study, we looked for the role of the MICA and HLA-Cw genes polymorphisms in PsA pathogenesis. We investigated 100 PsA patients and 94 healthy Czech individuals. We...
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