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Article

The region of 150 kb telometic to HLA-C is associated with psoriasis in the Jewish population.

The Journal of investigative dermatology - 1 Nov 2005

Martínez-Borra Jesús, Brautbar Chaim, González Segundo, Enk Claes D, López-Vázquez Antonio, López-Larrea Carlos

Abstract excerpt

The HLA-Cw*0602 has been associated with psoriasis in different ethnic groups. But, it remains unclear whether HLA-C is the PSORS1 gene (the psoriasis gene in the MHC). Thus, several case-control studies have been performed in order to investigate whether HLA-C itself determines the susceptibility to the disease. We studied 59 Jewish patients with type I psoriasis and 79 matched controls. Polymorphic genes and...

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Source

Identifiers

PMID: 16297191
DOI: 10.1111/j.0022-202X.2005.23892.x

Genes

CDSN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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The region of 150 kb telometic to HLA-C is associated with psoriasis in the Jewish population.PMID 16297191Read ↗

Psoriasis vulgaris and psoriatic arthritis share a 100 kb susceptibility region telomeric to HLA-C.Semantic proximity Read ↗

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Genetic aspects of psoriasis.Semantic proximity Read ↗

Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene.Semantic proximity Read ↗

An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element.Semantic proximity Read ↗

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