Article
A study of candidate genes for psoriasis near HLA-C in Chinese patients with psoriasis.
The British journal of dermatology - 1 Mar 2003
Chang Y T, Tsai S F, Lee D D, Shiao Y M, Huang C Y, Liu H N, Wang W J, Wong C K
Abstract excerpt
BACKGROUND: Genetic analyses have identified the HLA-Cw6 allele as the major risk allele for psoriasis in many racial groups. However, by serological typing, HLA-Cw6 is not considered a risk factor in Chinese psoriatics. There are several susceptibility genes for psoriasis residing in chromosome 6p near the HLA-C locus, including the corneodesmosin (CDSN) gene, the octamer transcription factor-3 (POU5F1) gene,...
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