Molecular biology of the MEN2 gene.

doi:10.1046/j.1365-2796.1998.00330.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Molecular biology of the MEN2 gene.

Journal of internal medicine - 1 Jun 1998

Santoro M, Melillo R M, Carlomagno F, Visconti R, De Vita G, Salvatore G, Lupoli G, Fusco A, Vecchio G

Abstract excerpt

Cancer is a genetic disease caused by 'gain of function' mutations of oncogenes and 'loss of function' mutations of tumour suppressors and of genes involved in DNA repair mechanisms. The RET gene encodes a tyrosine kinase receptor for molecules belonging to the glial cell line-derived neurotrophi...

Topics

Carcinoma, Papillary
Drosophila Proteins
Glial Cell Line-Derived Neurotrophic Factor Receptors
Humans
Multiple Endocrine Neoplasia Type 2a
Mutation
Protein-Tyrosine Kinases
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-ret
Receptor Protein-Tyrosine Kinases
Signal Transduction
Thyroid Neoplasms

Source

Open in PubMed

Identifiers

PMID: 9681850
DOI: 10.1046/j.1365-2796.1998.00330.x

Genes

RET
GDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9681850-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics