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Article

Molecular advances in medullary thyroid cancer diagnostics.

Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2006

Hubner Richard A, Houlston Richard S

Abstract excerpt

Germline activating mutations in the RET proto-oncogene cause inherited medullary thyroid cancer (MTC) and the multiple endocrine neoplasia type 2 (MEN2) syndrome. Identification of a RET mutation in an individual with MEN2 allows pre-symptomatic genetic testing of other at-risk family members, and guides early intervention to prevent death and serious morbidity from MTC. Developments in the understanding of...

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Identifiers

PMID: 16519882
DOI: 10.1016/j.cca.2006.01.029

Genes

RET

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Source receipt: pubmed, retrieved 7 Sept 2026.

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