Article
Cancers connected with mutations in RET proto-oncogene.
Neoplasma - 1 Jan 2001
Altanerová V
Abstract excerpt
Germline mutations of RET proto-oncogene are connected with inherited cancer syndrome multiple endocrine neoplasia type 2. The syndrome is characterized by incidence of medullary thyroid carcinoma frequently associated with pheochromocytoma and hyperparathyroidism. Genetic testing of family members at risk significantly contributed to diagnosis and management of MEN 2. Early genetic screening for RET mutations...
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