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Article

Linkage disequilibrium and haplotype mapping of a skin cancer susceptibility locus in outbred mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 2000

Peissel B, Zaffaroni D, Zanesi N, Zedda I, Manenti G, Rebessi S, Pazzaglia S, Doria G, Covelli V, Dragani T A, Saran A

Abstract excerpt

Car-R (carcinogenesis-resistant) and Car-S (carcinogenesis-susceptible) outbred mice, obtained by phenotypic selection from an initial intercross of eight inbred strains, show a >100-fold difference in their susceptibility to two-stage skin tumorigenesis. We found that the lines carry a high degree of genetic polymorphism. with an average heterozygosity of 0.39. This polymorphism allowed the use of linkage...

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Identifiers

PMID: 11063253
DOI: 10.1007/s003350010184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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