Article
A gated channel into the proteasome core particle.
Nature structural biology - 1 Nov 2000
Groll M, Bajorek M, Köhler A, Moroder L, Rubin D M, Huber R, Glickman M H, Finley D
Abstract excerpt
The core particle (CP) of the yeast proteasome is composed of four heptameric rings of subunits arranged in a hollow, barrel-like structure. We report that the CP is autoinhibited by the N-terminal tails of the outer (alpha) ring subunits. Crystallographic analysis showed that deletion of the tai...
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