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Article

Proteasome disassembly and downregulation is correlated with viability during stationary phase.

Current biology : CB - 1 Jul 2003

Bajorek Monika, Finley Daniel, Glickman Michael H

Abstract excerpt

During prolonged starvation, yeast cells enter a stationary phase (SP) during which the synthesis of many proteins is dramatically decreased. We show that a parallel decrease in proteasome-dependent proteolysis also occurs. The reduction in proteolysis is correlated with disassembly of 26S proteasome holoenzymes into their 20S core particle (CP) and 19S regulatory particle (RP) components. Proteasomes are...

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PMID: 12842014
DOI: 10.1016/s0960-9822(03)00417-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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