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Article

Interindividual variation in CYP1A1 expression in breast tissue and the role of genetic polymorphism.

Carcinogenesis - 1 Nov 2000

Goth-Goldstein R, Stampfer M R, Erdmann C A, Russell M

Abstract excerpt

The cytochrome P4501A1 (CYP1A1) enzyme is regulated at the transcriptional level and its expression is influenced by genetic factors, polymorphisms in the structural and regulatory genes, and by environmental factors such as exposure to polycyclic aromatic hydrocarbons (PAHs). To investigate the role of CYP1A1 in breast cancer, we studied CYP1A1 expression in breast tissue, thereby taking all possible modifying...

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PMID: 11062177
DOI: 10.1093/carcin/21.11.2119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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