Article
CYP1A1.
IARC scientific publications - 1 Jan 1999
Kawajiri K
Abstract excerpt
CYP1A1 plays an important role in the metabolism of polycyclic hydrocarbons that occur in the environment and several studies suggest that the genetic polymorphism of the gene may play a role in the predisposition to cancer. In order to evaluate the function of CYP1A1 in vivo as a host factor determinant of environmentally-caused cancers in humans, additional investigations are needed involving not only molecular...
Topics
- Animals
- Cytochrome P-450 CYP1A1
- Environmental Exposure
- Genetic Predisposition to Disease
- Genetics, Population
- Genotype
- Humans
- Mice
- Molecular Epidemiology
- Neoplasms, Experimental
- Phenotype
- Polycyclic Compounds
- Polymorphism, Genetic
