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Article

Deficient DNA repair capacity: a predisposing factor and high risk predictive marker in familial colorectal cancer.

Journal of experimental & clinical cancer research : CR - 1 Mar 1999

Ankathil R, Jyothish B, Madhavan J, Nair M K

Abstract excerpt

Even though colorectal cancer tends to aggregate in families, there is paucity of information on the genetic determinism for familial colorectal cancer (FCRC) predisposition. Therefore, we investigated constitutional chromosome abnormalities and bleomycin induced chromosome sensitivity of 26 familial and 30 sporadic colorectal cancer (SCRC) patients, 60 unaffected family members (first/second degree relatives)...

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PMID: 10374674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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