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Article

Chromosomal mutagen sensitivity associated with mutations in BRCA genes.

Cytogenetic and genome research - 1 Jan 2004

Speit G, Trenz K

Abstract excerpt

Chromosomal mutagen sensitivity is a common feature of cells from patients with different kinds of cancer. A portion of breast cancer patients also shows an elevated sensitivity to the induction of chromosome damage in cells exposed to ionizing radiation or chemical mutagens. Segregation analysis in families of patients with breast cancer indicated heritability of mutagen sensitivity. It has therefore been...

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Source

Identifiers

PMID: 15162060
DOI: 10.1159/000077511

Genes

BRCA1
BRCA2
MNT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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