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Article

IgA and IgM V(H) repertoires in human colon: evidence for clonally expanded B cells that are widely disseminated.

Gastroenterology - 1 Nov 2000

Holtmeier W, Hennemann A, Caspary W F

Abstract excerpt

BACKGROUND & AIMS: The mucosal immune system defends the body from pathogens to which the mucosal surfaces are continually exposed. Because lamina propria B cells should reflect the antigenic experience of the gut, we investigated their immunoglobulin (Ig) repertoire and distribution. METHODS: The junctional diversity of the IgA and IgM heavy-chain transcripts in the colon and the peripheral blood of healthy...

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Identifiers

PMID: 11054383
DOI: 10.1053/gast.2000.20219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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