Article
Tissue-specific expressed antibody variable gene repertoires.
PloS one - 1 Jan 2014
Briney Bryan S, Willis Jordan R, Finn Jessica A, McKinney Brett A, Crowe James E
Abstract excerpt
Recent developments in genetic technologies allow deep analysis of the sequence diversity of immune repertoires, but little work has been reported on the architecture of immune repertoires in mucosal tissues. Antibodies are the key to prevention of infections at the mucosal surface, but it is currently unclear whether the B cell repertoire at mucosal surfaces reflects the dominant antibodies found in the systemic...
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