Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypermutation, diversity and dissemination of human intestinal lamina propria plasma cells.

European journal of immunology - 1 Nov 1997

Dunn-Walters D K, Boursier L, Spencer J

Abstract excerpt

In this work we have microdissected lamina propria plasma cells and used polymerase chain reaction and sequencing to investigate immunoglobulin (Ig) gene rearrangements and mutations in human intestine. In addition, specific primers were designed for individual Ig gene rearrangements to analyze the distribution of related B cell and plasma cell clones at different sites along the bowel. Confirming our earlier...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Base Sequence

Share to Infant

Share to Molecular Sequence Data

Source

Identifiers

PMID: 9394824
DOI: 10.1002/eji.1830271131

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypermutation, diversity and dissemination of human intestinal lamina propria plasma cells.PMID 9394824Read ↗

Characteristics of IgVH genes used by human intestinal plasma cells from childhood.Semantic proximity Read ↗

Sequence analysis of human IgV<sub>H</sub> genes indicates that ileal lamina propria plasma cells are derived from Peyer's patchesSemantic proximity Read ↗

Human IgA- and IgM-secreting intestinal plasma cells carry heavily mutated VH region genes.Semantic proximity Read ↗

IgA and IgM V(H) repertoires in human colon: evidence for clonally expanded B cells that are widely disseminated.Semantic proximity Read ↗

Sequence analysis of light chain genes from human intestinal plasma cells demonstrates that lambda genes are almost all in-frame and highly mutated and most kappa genes are highly mutated when in-frame and minimally mutated when out-of-frame.Semantic proximity Read ↗

Immunoglobulin genes from human duodenal and colonic plasma cells are mutated.Semantic proximity Read ↗

Remodeling of human colon plasma cell repertoire in ulcerative colitisSemantic proximity Read ↗

IgA Plasma Cells Are Long-Lived Residents of Gut and Bone Marrow That Express Isotype- and Tissue-Specific Gene Expression Patterns.Semantic proximity Read ↗

Evidence for Local Expansion of IgA Plasma Cell Precursors in Human IleumSemantic proximity Read ↗

B cell development and proliferation of mature B cells in human fetal intestine.Semantic proximity Read ↗

Monoclonal immunoglobulin A derived from peritoneal B cells is encoded by both germ line and somatically mutated VH genes and is reactive with commensal bacteria.Semantic proximity Read ↗

Human colorectal cancer cells frequently express IgG and display unique Ig repertoireSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.