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Article

Mannose-binding lectin is a component of innate mucosal defense against Cryptosporidium parvum in AIDS.

Gastroenterology - 1 Nov 2000

Kelly P, Jack D L, Naeem A, Mandanda B, Pollok R C, Klein N J, Turner M W, Farthing M J

Abstract excerpt

BACKGROUND & AIMS: Nonimmune mechanisms of mucosal defense seem to be biologically important and might explain the observed variability in the course of enteric infection in immunodeficiency. Mannose-binding lectin (MBL) deficiency is associated with persistent diarrhea in children. We found that genetic determinants of MBL deficiency appear to predispose to cryptosporidiosis in patients with the acquired...

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Identifiers

PMID: 11054381
DOI: 10.1053/gast.2000.19573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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