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Article

Heterogeneity in the clinical phenotype of TP53 mutations in breast cancer patients.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2000

Alsner J, Yilmaz M, Guldberg P, Hansen L L, Overgaard J

Abstract excerpt

TP53 mutation is a strong independent marker for survival in breast cancer with some heterogeneity in the clinical phenotype of various types of mutations. Based on 315 patients with breast carcinoma, we suggest a new model for the differentiation of TP53 mutations. Although TP53 mutation in general was associated with aggressive tumor/patient characteristics, missense mutations outside any conserved or...

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Identifiers

PMID: 11051239
DOI: 10.1186/bcr109
PMCID: PMC3300808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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