TP53 mutations in breast cancer: association with ductal histology and early relapse of disease.

doi:10.1177/172460080802300303

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Article

TP53 mutations in breast cancer: association with ductal histology and early relapse of disease.

The International journal of biological markers - 1 Jan 2000

Brankovic-Magic M V, Jankovic R N, Dobricic J D, Borojevic N D, Magic Z M, Radulovic S S

Abstract excerpt

PURPOSE: This study aimed to investigate the incidence of core domain TP53 mutations in Serbian breast cancer patients in view of their possible correlation with prognostic parameters, tumor characteristics and clinical disease course. METHODS: 145 breast cancer patients were included. Data on clinical disease course were available for 100 patients including 30 node-negative and 70 node-positive patients. After...

Topics

Adult
Aged
Breast Neoplasms
Case-Control Studies
Disease-Free Survival
Female
Genes, p53
Humans
Middle Aged
Mutation
Polymorphism, Single-Stranded Conformational
Receptors, Steroid
Recurrence
Serbia
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 18949740
DOI: 10.1177/172460080802300303

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