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Article

TP53 mutations and breast cancer prognosis: particularly poor survival rates for cases with mutations in the zinc-binding domains.

Genes, chromosomes & cancer - 1 Sept 1995

Børresen A L, Andersen T I, Eyfjörd J E, Cornelis R S, Thorlacius S, Borg A, Johansson U, Theillet C, Scherneck S, Hartman S

Abstract excerpt

Acquired mutations in TP53 as well as immunohistochemically detectable protein expression have been implicated as prognostic factors for breast cancer. We have evaluated the relationship between mutations detected in 119 breast tumours and various clinicohistopathological indices, stratifying the mutations according to the functional domains as defined by the recent elucidation of the crystal structure of the...

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Identifiers

PMID: 8527388
DOI: 10.1002/gcc.2870140113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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