Article
Overexpression of DA41 in v-Ha-ras-3Y1 cells causes growth suppression.
Japanese journal of cancer research : Gann - 1 Oct 2000
Ozaki T, Nakamura Y, Hanaoka E, Nakagawara A, Sakiyama S
Abstract excerpt
We have recently found that DA41 exhibits marked homology with mouse PLIC-1, PLIC-2, frog XDRP1 and yeast DSK2. XDRP1 has been shown to be associated with cyclin A, and blocks cell division of frog embryo. In the present study, we examined the biological role(s) of DA41 in mammalian cells by overexpressing it in v-Ha-ras-transformed 3Y1 cells (ras-3Y1). Transfectants which expressed a high level of DA41 mRNA...
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