Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Constitutive expression of thymidylate synthase from LCDV-C induces a transformed phenotype in fish cells.

Virology - 1 Mar 2008

Zhao Zhe, Shi Yan, Ke Fei, Wei Sun, Gui Jianfang, Zhang Qiya

Abstract excerpt

Thymidylate synthase (TS), an essential enzyme in DNA synthesis and repair, plays a key role in the events of cell cycle regulation and tumor formation. Here, an investigation was presented about subcellular location and biological function of viral TS from lymphocystis disease virus from China (LCDV-C) in fish cells. Fluorescence microscopy revealed that LCDV-C TS was predominantly localized in the cytoplasm in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Transformed
Share to Cell Proliferation
Share to Cell Transformation, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cells, Cultured

Share to Cyprinidae

Share to Cytoplasm

Share to Salmon

Share to Thymidylate Synthase

Source

Identifiers

PMID: 18037154
DOI: 10.1016/j.virol.2007.10.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Constitutive expression of thymidylate synthase from LCDV-C induces a transformed phenotype in fish cells.PMID 18037154Read ↗

Elevated Levels of Thymidylate Synthase Linked to Neoplastic Transformation of Mammalian CellsSemantic proximity Read ↗

Cytotoxic effect of cloned EGFP gene on NCI-H727 cell line via genetically engineered gene transfer systemSemantic proximity Read ↗

Identification of fish CMPK2 as an interferon stimulated gene against SVCV infectionSemantic proximity Read ↗

Primary Tree Shrew Dermis Fibroblasts Support Lytic Replication of Human CytomegalovirusSemantic proximity Read ↗

Development of pseudotyped retroviral system for effective gene transfer and expression in penaeid shrimp cellsSemantic proximity Read ↗

The peach latent mosaic viroid replication initiation site is located at a universal position that appears to be defined by a conserved sequence.Semantic proximity Read ↗

Identification and Characterization of a Shrimp White Spot Syndrome Virus (WSSV) Gene That Encodes a Novel Chimeric Polypeptide of Cellular-Type Thymidine Kinase and Thymidylate KinaseSemantic proximity Read ↗

Expression of recombinant classical swine fever virus E2 glycoprotein by endogenous Txnip promoter in stable transgenic CHO cellsSemantic proximity Read ↗

Nuclear localization of enzymatically active green fluorescent protein-CTP:phosphocholine cytidylyltransferase alpha fusion protein is independent of cell cycle conditions and cell types.Semantic proximity Read ↗

Tumor selective replication of Newcastle disease virus: Association with defects of tumor cells in antiviral defenceSemantic proximity Read ↗

Regulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytes.Semantic proximity Read ↗

In vivo and in vitro analyses of recombinant baculoviruses lacking a functional cg30 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.