Article
Following the LINEs: an analysis of primate genomic variation at human-specific LINE-1 insertion sites.
Molecular biology and evolution - 1 Aug 2003
Vincent Bethaney J, Myers Jeremy S, Ho Huei Jin, Kilroy Gail E, Walker Jerilyn A, Watkins W Scott, Jorde Lynn B, Batzer Mark A
Abstract excerpt
The L1 Ta subfamily of long interspersed elements (LINEs) consists exclusively of human-specific L1 elements. Polymerase chain reaction-based screening in nonhuman primate genomes of the orthologous sites for 249 human L1 Ta elements resulted in the recovery of various types of sequence variants for approximately 12% of these loci. Sequence analysis was employed to capture the nature of the observed variation and...
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