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Article

Long PCR detection of the C4A null allele in B8-C4AQ0-C4B1-DR3.

Journal of immunological methods - 20 Oct 2000

Grant S F, Kristjánsdóttir H, Steinsson K, Blöndal T, Yuryev A, Stefansson K, Gulcher J R

Abstract excerpt

The genes coding for the two components of complement 4 (C4), C4A and C4B, are located within the major histocompatibility complex (MHC) on the short arm of chromosome 6. Several studies have shown that deficiency of C4A is associated with systemic lupus erythematosus (SLE), rheumatoid arthritis and scleroderma. A large deletion covering most of the C4A gene and the 21-hydroxylase-A (21-OHA) pseudogene found on...

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PMID: 11033017
DOI: 10.1016/s0022-1759(00)00251-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Long PCR detection of the C4A null allele in B8-C4AQ0-C4B1-DR3.PMID 11033017Read ↗

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