Article
A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.
Lupus - 1 Jan 2007
Puah S M, Lian L H, Chew C H, Chua K H, Tan S Y
Abstract excerpt
The aim of the present study was to investigate the association of C4 gene mutations with systemic lupus erythematosus, in 130 Malaysian SLE patients and 130 healthy controls. Generally, various PCR approaches were used to screen the mutations of the C4 genes, which included 2 bp (+TC) insertions at codon 1213 in exon 29, 1 bp deletions (-C) at codon 811 in exon 20, 1 bp (-C), 2 bp (-GT) deletions at codons 522...
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