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Article

Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer.

Oncotarget - 7 Feb 2017

Segovia Cristina, Martínez-Fernández Mónica, Dueñas Marta, Rubio Carolina, López-Calderón Fernando F, Costa Clotilde, Saiz-Ladera Cristina, Fernández-Grajera María, Duarte José, Muñoz Huberto García, de la Rosa Federico, Villacampa Felipe, Castellano Daniel, Paramio Jesús M

Abstract excerpt

The high rates of tumor recurrence and progression represent a major clinical problem in non-muscle invasive bladder cancer. Previous data showed that EZH2-dependent signaling mediates these processes, whereas the frequent alterations of PIK3CA gene (copy gains and mutations) are predictive of re...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28060766
DOI: 10.18632/oncotarget.14453
PMCID: PMC5354678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-28060766-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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