Article
Patterns of chromosomal aberrations in urinary bladder tumours and adjacent urothelium
11 Jun 2002
Abstract excerpt
Bladder cancer is often characterized by recurrent and multifocal growth, and tumours are frequently accompanied by precancerous alterations of the surrounding urothelium. These findings have led to the hypothesis that cells from areas of genetically aberrant but morphologically non-cancerous or even unremarkable mucosa may be the source of bladder carcinomas. Fluorescence in situ hybridization (FISH) was...
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