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Article

Genetic aberrations of c-myc and CCND1 in the development of invasive bladder cancer

1 Sept 2002

Abstract excerpt

Detrusor muscle invasive transitional cell carcinoma is associated with poor prognosis and is responsible for the majority of bladder cancer related deaths. Amplifications of c-myc and CCND1 are associated with detrusor-muscle-invasive transitional cell carcinoma, however, their precise role in driving disease progression is unclear. Fluorescence in situ hybridisation on archival tissue from 16 patients with...

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PMID: 12237776
DOI: 10.1038/sj.bjc.6600531

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