Article
Agonist-induced isometric contraction of smooth muscle cell-populated collagen gel fiber.
American journal of physiology. Cell physiology - 1 Nov 2000
Oishi K, Itoh Y, Isshiki Y, Kai C, Takeda Y, Yamaura K, Takano-Ohmuro H, Uchida M K
Abstract excerpt
String-shaped reconstituted smooth muscle (SM) fibers were prepared in rectangular wells by thermal gelation of a mixed solution of collagen and cultured SM cells derived from guinea pig stomach. The cells in the fiber exhibited an elongated spindle shape and were aligned along the long axis. The fiber contracted in response to KCl (140 mM), norepinephrine (NE; 10(-7) M), epinephrine (10(-7) M), phenylephrine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.