Article
Contractility and phenotype transitions in serosal thickening of obstructed rabbit bladder.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Apr 1995
Roelofs M, Wein A J, Monson F C, Passerini-Glazel G, Koteliansky V E, Sartore S, Levin R M
Abstract excerpt
Partial outlet obstruction of rabbit bladder induces serosal thickening and smooth muscle (SM) cell hypertrophy that are accompanied by phenotypic changes in the expression of cytoskeletal and cytocontractile proteins. In the present study, we compare the observed progressive phenotypic changes w...
Topics
- Animals
- Bethanechol
- Cytoskeletal Proteins
- Cytoskeleton
- Fluorescent Antibody Technique
- Immunohistochemistry
- Muscle Contraction
- Muscle, Smooth
- Phenotype
- Potassium Chloride
- Rabbits
- Receptors, Muscarinic
- Urinary Bladder Neck Obstruction