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Article

Bladder smooth muscle organ culture preparation maintains the contractile phenotype.

American journal of physiology. Renal physiology - 1 Nov 2012

Wang Tanchun, Kendig Derek M, Chang Shaohua, Trappanese Danielle M, Chacko Samuel, Moreland Robert S

Abstract excerpt

Smooth muscle cells, when subjected to culture, modulate from a contractile to a secretory phenotype. This has hampered the use of cell culture for molecular techniques to study the regulation of smooth muscle biology. The goal of this study was to develop a new organ culture model of bladder smooth muscle (BSM) that would maintain the contractile phenotype and aid in the study of BSM biology. Our results showed...

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Source

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Identifiers

PMID: 22896042
DOI: 10.1152/ajprenal.00261.2011
PMCID: PMC3518193

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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