Article
A knockout screen for protein kinases required for the proper meiotic segregation of chromosomes in the fission yeast Schizosaccharomyces pombe.
Cell cycle (Georgetown, Tex.) - 15 Feb 2013
Kovacikova Ines, Polakova Silvia, Benko Zsigmond, Cipak Lubos, Zhang Lijuan, Rumpf Cornelia, Miadokova Eva, Gregan Juraj
Abstract excerpt
The reduction of chromosome number during meiosis is achieved by two successive rounds of chromosome segregation after just single round of DNA replication. To identify novel proteins required for the proper segregation of chromosomes during meiosis, we analyzed the consequences of deleting Schizosaccharomyces pombe genes predicted to encode protein kinases that are not essential for cell viability. We show that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
