Article
Ku70 can translocate to the nucleus independent of Ku80 translocation and DNA-PK autophosphorylation.
Biochemical and biophysical research communications - 5 Oct 2000
Koike M, Shiomi T, Koike A
Abstract excerpt
Ku plays an important role in multiple nuclear processes, e.g., DNA repair, chromosome maintenance, and transcriptional regulation. Although some evidence suggests that the nuclear translocation of Ku plays a key role in regulating the function of Ku, the mechanism is poorly understood. Using the site-directed mutagenesis technique, we demonstrate here that Ku70 can translocate to the nucleus without...
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