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Article

Rapid determination of short DNA sequences by the use of MALDI-MS.

Nucleic acids research - 15 Oct 2000

Nordhoff E, Luebbert C, Thiele G, Heiser V, Lehrach H

Abstract excerpt

We have developed a protocol for rapid sequencing of short DNA stretches (15-20 nt) using MALDI-TOF-MS. The protocol is based on the Sanger concept with the modification that double-stranded template DNA is used and all four sequencing reactions are performed in one reaction vial. The sequencing products are separated and detected by MALDI-TOF-MS and the sequence is determined by comparing measured molecular mass...

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Identifiers

PMID: 11024188
DOI: 10.1093/nar/28.20.e86
PMCID: PMC110802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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