Article
DNA analysis by MALDI-TOF mass spectrometry.
Human mutation - 1 May 2004
Gut Ivo Glynne
Abstract excerpt
The last decade has seen an increased demand for high-throughput DNA analysis. This is mainly due to the human genome sequencing project that is now completed. Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry was pinpointed early on as a technology that could be of great use for sequence variation analysis in the post-genome sequencing era. Applications developed first on...
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