Article
Apolipoprotein genotype for prediction of Alzheimer's disease in older Japanese: the Hisayama Study.
Journal of the American Geriatrics Society - 1 Jun 2011
Ohara Tomoyuki, Ninomiya Toshiharu, Kubo Michiaki, Hirakawa Yoichiro, Doi Yasufumi, Hata Jun, Iwaki Toru, Kanba Shigenobu, Kiyohara Yutaka
Abstract excerpt
OBJECTIVES: To estimate the effects of the apolipoprotein E (APOE)-ɛ4 allele on the development of dementia and to elucidate its usefulness in the risk prediction of dementia in Japanese. DESIGN: Prospective cohort study. SETTING: The Hisayama Study, in Japan. PARTICIPANTS: Five hundred twenty-three participants with deoxyribonucleic acid samples from a population of 1,073 community-dwelling participants without...
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