Article
Cognitive asymmetries associated with apolipoprotein E genotype in patients with Alzheimer's disease.
Journal of the International Neuropsychological Society : JINS - 1 Jul 2003
Finton Michael J, Lucas John A, Rippeth Julie D, Bohac Daryl L, Smith Glenn E, Ivnik Robert J, Petersen Ronald C, Graff-Radford Neill R
Abstract excerpt
The relationship between apolipoprotein E (apoE) genotype and cognitive performance was examined in 200 patients with probable Alzheimer's disease (AD). Differences between composite measures of verbal and nonverbal functioning were used to define asymmetric patterns of cognition. Patients who were homozygous for apoE epsilon4 demonstrated relatively worse nonverbal as compared to verbal cognitive ability. In...
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