Article
Apo E genotype, diabetes, and peripheral arterial disease in older men: the Honolulu Asia-aging study.
Genetic epidemiology - 1 Jul 2000
Resnick H E, Rodriguez B, Havlik R, Ferrucci L, Foley D, Curb J D, Harris T B
Abstract excerpt
The epsilon4 allele of the gene coding for apolipoprotein (apo) E is associated with an atherogenic lipid profile that has been linked to increased risk of coronary artery disease (CAD). Apo E genotype may also be associated with peripheral arterial disease (PAD). If present, this association may be modified by diabetes, which is also associated with dyslipidemia that predisposes to macrovascular disease....
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