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Article

Association of apolipoprotein E phenotypes with late onset Alzheimer's disease: population based study.

BMJ (Clinical research ed.) - 10 Sept 1994

Kuusisto J, Koivisto K, Kervinen K, Mykkänen L, Helkala E L, Vanhanen M, Hänninen T, Pyörälä K, Kesäniemi Y A, Riekkinen P

Abstract excerpt

OBJECTIVE: To determine the association between the e4 allele of apolipoprotein E and Alzheimer's disease in a randomly selected population sample. DESIGN: Cross sectional population based study. SUBJECTS: 980 people aged 69 to 78 (349 men, 631 women). SETTING: Population of Kuopio, eastern Finla...

Topics

Aged
Alleles
Alzheimer Disease
Apolipoproteins E
Cross-Sectional Studies
Dementia, Multi-Infarct
Female
Finland
Gene Frequency
Humans
Male
Odds Ratio

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Population Surveillance

Prevalence

Random Allocation

Sex Distribution

Source

Open in PubMed Open full text

Identifiers

PMID: 8086986
DOI: 10.1136/bmj.309.6955.636
PMCID: PMC2541512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8086986-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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