Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population-based mapping of pulmonary adenoma susceptibility 1 locus.

Cancer research - 15 Sept 2000

Dragani T A, Hirohashi S, Juji T, Kawajiri K, Kihara M, Ono-Kihara M, Manenti G, Nomoto T, Sugimura H, Genka K, Yokota J, Takahashi T, Mitsudomi T, Nagao M

Abstract excerpt

Pulmonary adenoma susceptibility 1 (Pas1), the major locus affecting inherited predisposition to lung tumor development in mice, maps near the Kras2 gene. We previously reported a significant association between a KRAS2/RsaI polymorphism and the risk and prognosis of lung adenocarcinoma (ADCA) in the Italian population. In the present case-control study, we examined 269 lung ADCA patients, 121 squamous cell lung...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Deoxyribonucleases, Type II Site-Specific

Share to Pilot Projects

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins p21(ras)

Share to ras Proteins

Share to Survival Analysis

Source

Identifiers

PMID: 11016621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population-based mapping of pulmonary adenoma susceptibility 1 locus.PMID 11016621Read ↗

Predisposition to lung tumorigenesis.Semantic proximity Read ↗

Genetic mapping of cancer susceptibility/resistance loci in the mouse.Semantic proximity Read ↗

Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines.Semantic proximity Read ↗

Localization of a human lung adenocarcinoma susceptibility locus, possibly syntenic to the mouse Pas1 locus, in the vicinity of the D12S1034 locus on chromosome 12p11.2-p12.1.Semantic proximity Read ↗

Mouse pulmonary adenoma susceptibility 1 locus is an expression QTL modulating Kras-4A.Semantic proximity Read ↗

Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice.Semantic proximity Read ↗

Genome-wide identification of functional polymorphisms modulating individual risk and prognosis of lung cancerSemantic proximity Read ↗

Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice.Semantic proximity Read ↗

A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice.Semantic proximity Read ↗

Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice.Semantic proximity Read ↗

Association of chromosome 12p genetic polymorphisms with lung adenocarcinoma risk and prognosis.Semantic proximity Read ↗

Fine mapping and candidate gene analyses of pulmonary adenoma resistance 1, a major genetic determinant of mouse lung adenoma resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.