Article
Association of chromosome 12p genetic polymorphisms with lung adenocarcinoma risk and prognosis.
Carcinogenesis - 1 Oct 1997
Manenti G, De Gregorio L, Pilotti S, Falvella F S, Incarbone M, Ravagnani F, Pierotti M A, Dragani T A
Abstract excerpt
The mapping near Kras2 of pulmonary adenoma susceptibility 1 (Pas1), a major locus affecting inherited predisposition to lung cancer in mice prompted us to test the homologous human region (12p12) for association with lung adenocarcinoma, by a population-based study. We genotyped 213 lung adenocarcinoma patients and 219 healthy blood donor subjects for five polymorphic markers mapping in the putative region of...
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